Indications for use: Symptomatic treatment of acute pain of moderate to severe intensity in cases where oral administration of the drug is inappropriate, such as postoperative pain, renal colic and low back pain.

Contraindication:
- Increased sensitivity to dexketoprofen, any other NSAIDs, or excipients of the drug;
- If substances with a similar action, such as acetylsalicylic acid or other NSAIDs, provoke the development of bronchial asthma attacks, bronchospasm, acute rhinitis, or cause the development of nasal polyps, urticaria, or angioedema;
- If photoallergic or phototoxic reactions occurred during treatment with ketoprofen or fibrates;
- In case of gastrointestinal bleeding or perforation in the medical history associated with previous NSAID therapy;
- In patients with active peptic ulcers/gastrointestinal bleeding or a history of gastrointestinal bleeding, ulcers, or perforations;- In patients with chronic dyspepsia;
- During active bleeding or with increased bleeding tendency;
- In Crohn’s disease or ulcerative colitis;
- In cases of severe heart failure;
- In moderate or severe renal dysfunction (creatinine clearance ≤59 ml/min);
- In severe liver dysfunction (10–15 points on the Child-Pugh scale);
- In hemorrhagic diathesis or other coagulation disorders;
- In cases of severe dehydration (due to vomiting, diarrhea, or inadequate fluid intake);
- During the third trimester of pregnancy and breastfeeding.
Due to the ethanol content in the drug, it is contraindicated for neuraxial (intrathecal or epidural) administration.